| 潘寻,苏都,苏佰礼,贲伟伟.围场县马铃薯中典型药物污染特征及健康风险评价[J].农业环境科学学报,2019,38(1):29-36. |
| 围场县马铃薯中典型药物污染特征及健康风险评价 |
| Pollution characteristics and health risk assessment of typical pharmaceuticals in potatoes of Weichang County, China |
| 投稿时间：2018-04-05 |
| DOI：10.11654/jaes.2018-0443 |
| 中文关键词: 围场 马铃薯 药物 健康风险评价 |
| 英文关键词: Weichang potato pharmaceuticals health risk assessment |
| 基金项目:国家自然科学基金项目（51678559） |
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| 摘要点击次数: 2042 |
| 全文下载次数: 1629 |
| 中文摘要: |
| 为掌握典型药物在农作物中的污染特征及健康风险，保障农产品质量安全，利用超声萃取-固相萃取-高效液相色谱/串联质谱（LC-MS/MS）技术，对围场县全县马铃薯中5大类（磺胺类、四环素类、氟喹诺酮类、大环内酯类及其他类）25种药物污染水平及富集效果进行了调查，并对健康风险进行了评价。结果表明，有20种目标物被检出，不同目标物检出率差异显著，检出含量范围为0.13~3.67 μg·kg-1，单种污染物最高检出含量为17.0 μg·kg-1。马铃薯对目标污染物的富集系数范围在0.01~39.6之间，最大富集系数为61.8。畜禽粪便是马铃薯中药物残留的主要来源，尽管整体检出水平和健康风险相对较低，但长期摄入与协同作用引发的潜在健康风险不容忽视。因此，仍需严控污染源头，推进畜禽粪便安全资源化利用，确保农田环境质量及农产品安全品质。 |
| 英文摘要: |
| In order to understand the pollution characteristics and health risk of typical pharmaceuticals in crops and guarantee the safety of agricultural products, the concentrations of 25 pharmaceuticals, which belong to the sulfonamide, tetracycline, fluoroquinolone, macrolide, and other categories, in potato samples from Weichang County were investigated using ultrasonic extraction, solid-phase extraction, and high performance liquid chromatography/tandem mass spectrometry(LC-MS/MS). The enrichment coefficient was calculated, and health risk assessment was conducted. The results show that 20 pharmaceuticals were detected, with median concentrations ranging from 0.13 to 3.67 μg·kg-1 and the highest concentration of a single pharmaceutical 17.0 μg·kg-1. Median enrichment coefficients of the pharmaceuticals in potato ranged from 0.01 to 39.6, with the highest value 61.8. Livestock manure was the main source of residual pharmaceuticals in potato, and the peculiarity of local traditional farming practices led to the tendency for accumulation of pharmaceuticals. Although the overall concentration level and health risk were relatively low, the potential health risk caused by long-term intake and synergistic effects could not be ignored. Therefore, it is necessary to strictly control the source of pharmaceuticals and promote the safe utilization of livestock manure, thus ensuring the environmental quality of cropland and the safety of agricultural products. |
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