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| The Toxic Effects of Imidacloprid on Japanese Quail |
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| KeyWord:imidacloprid; Japanese quail; toxicity; toxicological effects |
| Author Name | Affiliation | | DENG Zhao-rong | Research Center of Pesticide Environmental Toxicology, College of Plant Protection, Shandong Agricultural University | | WANG Meng | Research Center of Pesticide Environmental Toxicology, College of Plant Protection, Shandong Agricultural University | | GUAN Lei | Research Center of Pesticide Environmental Toxicology, College of Plant Protection, Shandong Agricultural University | | MU Wei | Research Center of Pesticide Environmental Toxicology, College of Plant Protection, Shandong Agricultural University | | LIU Feng | Research Center of Pesticide Environmental Toxicology, College of Plant Protection, Shandong Agricultural University |
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| Abstract: |
| The acute and accumulation toxicities of imidacloprid on Japanese quail were determined by oral way or feeding exposure method, and the sub-chronic toxicological effects of imidacloprid were also evaluated according to the blood biochemical indicators. The results showed that the LD50 of oral acute toxicity was 30.25 mg·kg-1 bw, it belongs to high toxicity grade. The dietary LC50 was 1 455.11 mg·kg-1 feed and the toxicity level is low grade. The cumulative coefficient（K） was greater than 5, which belongs to a low-grade accumulation. At the later of sub-chronic toxicity period, the weight and food consumption were significantly reduced with the treatment of the middle and high concentration. The serum creatinine and uric acid of blood serum biochemical parameters were significantly increased compared with the control group. The liver organ coefficient of the treated quail with the high concentration was higher than the control group（P<0.01）. The maximum no-effect level（MNEL） of imidacloprid on Japanese quail was 29.10 mg·kg-1 feed, and the minimum effect level（MEL） was more than 72.76 mg·kg-1 feed. The main target organ of imidacloprid on the Japanese quail was liver and it was also harmful to kidney in a certain extent. |
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