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Application of plant molecular genetics in identification of genes related to heavy metals accumulation in crops
Received:March 11, 2018  
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KeyWord:molecular genetics;heavy metals;cadmium;rice
Author NameAffiliation
HUANG Xin-yuan State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China 
ZHAO Fang-jie State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing 210095, China 
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Abstract:
      With increasing contamination of heavy metals in paddy soils in China, exceedance of the national safe standard in food crops is widespread in some areas, especially Southern China. Minimizing the transfer of heavy metals from soil to eatable parts of food crops and thus ensure the safety of agricultural products is a top priority of agricultural production in China. Molecular breeding of crop varieties that accumulate less heavy metals in eatable parts to meet the national safe standard is one of effective and low-cost strategies that product safe product in contaminated soils. The breeding of crop varieties that accumulate less heavy metals in eatable parts is based on the identification and characterization of genes that involved the uptake, transport and allocation of heavy metals in crops. In this review, we take OsNRAMP5, OsHMA3 and CAL1 as examples, to describe the application of plant molecular genetics including the forward and reverse genetics in identification genes which are responsible for the accumulation of cadmium(Cd) in rice. The molecular mechanism of these genes underlying the Cd accumulation in rice and the potential application of these genes in molecular breeding of rice varieties with low Cd accumulation in grains are also discussed.