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| Pollution characteristics and health risk assessment of typical pharmaceuticals in potatoes of Weichang County, China |
| Received:April 05, 2018 |
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| KeyWord:Weichang;potato;pharmaceuticals;health risk assessment |
| Author Name | Affiliation | E-mail | | PAN Xun | Foreign Economic Cooperation Office, Ministry of Ecology and Environment of the People's Republic of China, Beijing 100035, China | | | SU Du | Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China | | | SU Bai-li | Environmental Monitoring Station of Jinan, Jinan 250101, China | | | BEN Wei-wei | Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China | wwben@rcees.ac.cn |
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| Abstract: |
| In order to understand the pollution characteristics and health risk of typical pharmaceuticals in crops and guarantee the safety of agricultural products, the concentrations of 25 pharmaceuticals, which belong to the sulfonamide, tetracycline, fluoroquinolone, macrolide, and other categories, in potato samples from Weichang County were investigated using ultrasonic extraction, solid-phase extraction, and high performance liquid chromatography/tandem mass spectrometry(LC-MS/MS). The enrichment coefficient was calculated, and health risk assessment was conducted. The results show that 20 pharmaceuticals were detected, with median concentrations ranging from 0.13 to 3.67 μg·kg-1 and the highest concentration of a single pharmaceutical 17.0 μg·kg-1. Median enrichment coefficients of the pharmaceuticals in potato ranged from 0.01 to 39.6, with the highest value 61.8. Livestock manure was the main source of residual pharmaceuticals in potato, and the peculiarity of local traditional farming practices led to the tendency for accumulation of pharmaceuticals. Although the overall concentration level and health risk were relatively low, the potential health risk caused by long-term intake and synergistic effects could not be ignored. Therefore, it is necessary to strictly control the source of pharmaceuticals and promote the safe utilization of livestock manure, thus ensuring the environmental quality of cropland and the safety of agricultural products. |
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