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Characterization and risk assessment of antibiotic contamination in sediments of Qingshitan Reservoir,Guilin City,China
Received:August 25, 2023  
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KeyWord:antibiotic;Qingshitan Reservoir;ecological risk;health risk
Author NameAffiliation
DONG Kun College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China
Collaborative Innovation Center for Water Pollution Control and Water Security in Karst Area, Guilin University of Technology, Guilin 541004, China 
TANG Yukun College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China 
ZHOU Xinyu College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China 
HUANG Haoyu College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China 
WANG Dunqiu College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China
Collaborative Innovation Center for Water Pollution Control and Water Security in Karst Area, Guilin University of Technology, Guilin 541004, China 
LI Haixiang College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541004, China
Collaborative Innovation Center for Water Pollution Control and Water Security in Karst Area, Guilin University of Technology, Guilin 541004, China 
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Abstract:
      To study the impact of antibiotic use on the ecology of reservoirs, Qingshitan Reservoir, the alternate drinking water source of Guilin City, was selected as the study area in October 2022. The contents of 17 antibiotics from the three major classes:sulfonamides, tetracyclines, and quinolones, in sediment samples from Qingshitan Reservoir were analyzed using solid-phase extraction and ultra-highperformance liquid chromatography-tandem mass spectrometry(UPLC-MS / MS) techniques. The results showed that the total concentration of the 20 sampling points ranged from 3.79 to 11.10 ng·L-1, and a total of 7 sulfonamide, 4 tetracycline, and 3 quinolone antibiotics were detected, with an average concentration of 0.084-1.26 ng·L-1. The most prevalent antibiotic was ofloxacin(OFL), which occurred at a concentration of 5.21 ng·L-1 and at the highest detection rate of 90%. The ecological and health risks of antibiotics in the Qingshitan Reservoir sediments were also assessed. The results showed that the risk entropy value(RQ)of the 17 antibiotics in the three major categories in the Qingshitan Reservoir sediments was less than 1, indicating a low risk. However, the maximum risk indicators at different sampling points pointed to OFL, highlighting the need to monitor the release of this particular antibiotic. The health risk assessment results indicate that the antibiotics in the Qingshitan Reservoir sediments do not pose a risk to human health.