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| Effects of Single and Combined Pollution of Three Common Sulfonamide Veterinary Drugs on Root Apical Cell Micronuclei of Different Crops |
| Received:October 27, 2014 |
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| KeyWord:sulfonamide;veterinary drugs;different plants;micronucleus;genotoxicity |
| Author Name | Affiliation | E-mail | | JIN Cai-xia | 1. Henan Key Laboratory of Environmental Pollution Control, Key Laboratory for Yellow River and Huaihe River Water Environmental and Pollution Control, Ministry of Education, School of Environment, Henan Normal University, Xinxiang 453007, China | | | MAO Lei | 1. Henan Key Laboratory of Environmental Pollution Control, Key Laboratory for Yellow River and Huaihe River Water Environmental and Pollution Control, Ministry of Education, School of Environment, Henan Normal University, Xinxiang 453007, China | maolei812@163.com | | SI Xiao-wei | 1. Henan Key Laboratory of Environmental Pollution Control, Key Laboratory for Yellow River and Huaihe River Water Environmental and Pollution Control, Ministry of Education, School of Environment, Henan Normal University, Xinxiang 453007, China | |
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| Abstract: |
| Genotoxicity of sulfadiazine(SD), sulfamonomethoxine(SMM) and sulfamethoxazole(SMZ) to crops was investigated under single and combined treatments. Five concentrations(1, 5, 10, 50, and 100 mg·L-1) of each of three veterinary drugs were generated by deionized water. Micronuclei of wheat, maize and broad bean root tips were counted by micronucleus test. All three sulfonamides induced micronucleus effects in the apical cells, illustrating the toxicity of sulfonamides to plant apical cells. Different plants had different sensitivity to three sulfonamides. In single SD or SMM treatment, plant sensitivity reduced in order of broad beans >maize >wheat, while the sensitivity to sulfonamide was broad beans >wheat >maize in the SMZ treatment. The promotion of single drug at low concentrations disappeared under combined pollution. The toxicity of combined sulfonamides was generally greater than that of single one. |
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