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Oxidative damage of cadmium on liver and gill of freshwater mussel Anodonta woodiana woodiana |
Received:October 10, 2016 |
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KeyWord:Anodonta woodiana woodiana;gill;liver;oxidative damage;cadmium |
Author Name | Affiliation | E-mail | YANG Hui-zhen | School of Life Science, Shanxi University, Taiyuan 030006, China | | LIU Na | School of Life Science, Shanxi University, Taiyuan 030006, China | | WEI Xiao-xi | School of Life Science, Shanxi University, Taiyuan 030006, China | | WANG Lan | School of Life Science, Shanxi University, Taiyuan 030006, China | lanwang@sxu.edu.cn |
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Abstract: |
In order to determine the oxidative damage in liver and gill of Anodonta woodiana woodiana by cadmium(Cd2+), this study designed five different concentration treatment groups which were 4.22, 8.43, 16.86, 33.72, 67.45 mg·L-1, according to the medial lethal concentration of Cd2+, as well as one control group. It were measured and analyzed of the contents of hydrogen peroxide, resistant ability of superoxide anion and hydroxyl radical in the gill and liver during 24, 48, 72 and 96 h. Furthermore, the capacity of total antioxidant of gill and liver were also monitored. The results showed that the contents of hydrogen peroxide increased significantly compared with the control group in the gill and liver, while the ability of resisting superoxide anion was decreased significantly(P<0.01). For inhibiting the hydroxyl radial, the liver and gill indicated different results, which showed that the gill had the notable lower ability while there was no significant difference found in liver. The findings of the experiments showed that liver was more sensitive to Cd2+ toxicity and liver could be as the target organ in Anodonta woodiana woodiana that could be used as the indicator organ for the water contamination. Moreover, the results indicated that the superoxide anion maybe the crucial factor for the oxidative damage of cadmium, so, it could be used as the biomarker for the cadmium contamination of freshwater. |
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