Advanced Search
Oxidative damage of cadmium on liver and gill of freshwater mussel Anodonta woodiana woodiana
Received:October 10, 2016  
View Full Text  View/Add Comment  Download reader
KeyWord:Anodonta woodiana woodiana;gill;liver;oxidative damage;cadmium
Author NameAffiliationE-mail
YANG Hui-zhen School of Life Science, Shanxi University, Taiyuan 030006, China  
LIU Na School of Life Science, Shanxi University, Taiyuan 030006, China  
WEI Xiao-xi School of Life Science, Shanxi University, Taiyuan 030006, China  
WANG Lan School of Life Science, Shanxi University, Taiyuan 030006, China lanwang@sxu.edu.cn 
Hits: 2808
Download times: 3095
Abstract:
      In order to determine the oxidative damage in liver and gill of Anodonta woodiana woodiana by cadmium(Cd2+), this study designed five different concentration treatment groups which were 4.22, 8.43, 16.86, 33.72, 67.45 mg·L-1, according to the medial lethal concentration of Cd2+, as well as one control group. It were measured and analyzed of the contents of hydrogen peroxide, resistant ability of superoxide anion and hydroxyl radical in the gill and liver during 24, 48, 72 and 96 h. Furthermore, the capacity of total antioxidant of gill and liver were also monitored. The results showed that the contents of hydrogen peroxide increased significantly compared with the control group in the gill and liver, while the ability of resisting superoxide anion was decreased significantly(P<0.01). For inhibiting the hydroxyl radial, the liver and gill indicated different results, which showed that the gill had the notable lower ability while there was no significant difference found in liver. The findings of the experiments showed that liver was more sensitive to Cd2+ toxicity and liver could be as the target organ in Anodonta woodiana woodiana that could be used as the indicator organ for the water contamination. Moreover, the results indicated that the superoxide anion maybe the crucial factor for the oxidative damage of cadmium, so, it could be used as the biomarker for the cadmium contamination of freshwater.