| 王振楠,白默涵,李晓晶,翁莉萍,叶会科.微生物降解四环素类抗生素的研究进展[J].农业环境科学学报,2022,41(12):2779-2786. |
| 微生物降解四环素类抗生素的研究进展 |
| Research progress on the microbial degradation of tetracycline antibiotics |
| 投稿时间：2022-11-21 修订日期：2022-12-08 |
| DOI：10.11654/jaes.2022-1188 |
| 中文关键词: 四环素 微生物降解 降解途径 降解机制 生物修复 |
| 英文关键词: tetracycline microbial degradation degradation pathway degradation mechanism bioremediation |
| 基金项目:中央级公益性科研院所基本科研业务费（2022-jbkyywf-yhk）；天津市自然科学基金项目（20JCYBJC01590） |
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| 中文摘要: |
| 随着抗生素在养殖行业使用加剧，施用粪肥导致的抗生素污染问题日趋严重，微生物降解抗生素作为解决这一问题的有效途径受到人们的广泛关注。本文综述了四环素类抗生素（TCs）的降解方法和微生物降解四环素类抗生素的研究现状，并对微生物降解四环素类抗生素的影响因素、降解路径以及其降解的分子机制进行了详细介绍。在此基础上，对微生物降解四环素类抗生素从实验室研究到实际生产应用进行了展望，指出了未来研究关注的重点。本文以期为人们深入认识四环素类抗生素的微生物修复提供参考，同时为四环素类抗生素的污染修复提供思路。 |
| 英文摘要: |
| With the intensification of the use of antibiotics in the aquaculture industry, the problem of antibiotic pollution caused by manure application is becoming increasingly serious. The use of microorganisms to degrade antibiotics in the environment is an effective strategy to address this problem, and it has attracted extensive attention. In this paper, the degradation methods of tetracycline antibiotics （TCs）and the research status of the microbial degradation of TCs are reviewed. Moreover, the influencing factors, degradation pathways, and molecular mechanisms of the microbial degradation of TCs are introduced in detail. On this basis, the microbial degradation of tetracycline from laboratory research to practical production and applications are discussed, and the focus of future research is suggested. This paper provides an in-depth understanding of the microbial remediation of tetracycline, and ideas for tetracycline pollution remediation. |
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